Neonatal Polycythemia

Relative Polycythemia—The Polycythemia of Stress *

In a group of normal subjects going from sea level to approximately 16,000 feet we observed that very soon after arrival at high altitude there was hemoconcentration, as indicated by an increased red cell count and hematocrit, but a normal total red cell volume and a low plasma volume. This "apparent increase" in the number of red blood cells in the early days after arrival at high altitude is,...

Symptomatic neonatal polycythemia: comparison of partial exchange transfusion with saline versus plasma.

A prospective study to evaluate efficacy and safety of partial exchange blood transfusion (PEBT) with normal saline or plasma was conducted in 30 symptomatic polycythemic newborns. Babies were randomly assigned to receive PEBT either with normal saline or plasma. Both groups were comparable in terms of birth weight, gestational age, preexchange hematocrit and viscosity. A significant fall in he...

Congenital polycythemia in Chuvashia.

Familial and congenital polycythemia, not due to high oxygen affinity hemoglobin or reduced 2,3-diphosphoglycerate in erythrocytes, is common in the Chuvash population of the Russian Federation. Hundreds of individuals appear to be affected in an autosomal recessive pattern. We studied six polycythemic Chuvash patients <20 years of age from unrelated families and 12 first-degree family members....

Muramidase in polycythemia vera.

Polycythemia vera: a review.

Polycythemia vera (PV) is a clonal stem cell disorder characterized by increased erythrocyte production. Its etiology is not fully understood, and hemorrhage, thrombosis, and hyperviscosity may occur at any time during the course of this disorder. Treatment depends on the most affected cell type, duration and severity of the condition, and patient age. PV treatment can involve phlebotomy, admin...